BPC-157 vs TB-500
Quick Answer
BPC-157 and TB-500 are both studied in tissue-repair research but act through different mechanisms. BPC-157 is a 15-amino-acid pentadecapeptide (CAS 137525-51-0) studied in cytoprotection and gut-barrier models. TB-500 is a Thymosin Beta-4 fragment (CAS 77591-33-4) studied in actin-regulation and angiogenesis research. In research designs they target complementary rather than identical pathways. Both are ≥99% HPLC-verified at Peptide.Express for in-vitro research only.
BPC-157 vs TB-500: At a Glance
| Attribute | BPC-157 | TB-500 |
|---|---|---|
| Mechanism class | Gastric pentadecapeptide (cytoprotection) | Thymosin Beta-4 fragment (actin regulation) |
| Peptide length | 15 amino acids (pentadecapeptide) | Fragment of 43-aa Thymosin Beta-4 |
| CAS number | 137525-51-0 | 77591-33-4 |
| Molecular weight | ~1419.5 Da | ~4963.4 Da |
| Molecular formula | C62H98N16O22 | C212H350N56O78S |
| Primary research area | Cytoprotection, gut-barrier models | Actin regulation, angiogenesis |
| Purity (Peptide.Express) | ≥99% HPLC verified | ≥99% HPLC verified |
How BPC-157 and TB-500 Differ in Research
BPC-157 and TB-500 are frequently compared in tissue-repair research, but they are mechanistically distinct. BPC-157 is a 15-amino-acid pentadecapeptide fragment of a gastric protein, studied in cytoprotection and gastrointestinal-barrier research. TB-500 is a synthetic fragment of Thymosin Beta-4, an actin-sequestering protein studied in angiogenesis and cell-migration models.
In research, the two compounds are tools for studying different aspects of the repair cascade. BPC-157 is investigated for cytoprotective and barrier-integrity mechanisms, while TB-500 is studied for actin dynamics and vascular remodeling. Some research designs investigate both compounds to study complementary tissue-repair pathways.
Peptide.Express supplies both at ≥99% HPLC-verified purity with a Certificate of Analysis. All material is for in-vitro laboratory research and educational use only.
Frequently Asked Questions
What is the main difference between BPC-157 and TB-500?
BPC-157 is a gastric pentadecapeptide studied in cytoprotection research, while TB-500 is a Thymosin Beta-4 fragment studied in actin-regulation and angiogenesis research. They target complementary rather than identical repair pathways. For laboratory research use only.
Can BPC-157 and TB-500 be studied together?
In research, BPC-157 and TB-500 are occasionally investigated together to study complementary tissue-repair mechanisms. BPC-157 targets cytoprotective pathways while TB-500 targets actin dynamics and angiogenesis. For in-vitro research use only.
Are both available at the same purity?
Yes. Both BPC-157 and TB-500 are HPLC-verified at ≥99% purity by independent third-party laboratories, with a Certificate of Analysis included with every order from Peptide.Express.