Buy CJC-1295+Ipamorelin NO DAC

CJC-1295+Ipamorelin NO DAC is a research peptide combination containing two growth hormone secretagogue compounds: CJC-1295 (a synthetic GHRH analog) and Ipamorelin (a pentapeptide GHS receptor agonist). The "NO DAC" designation indicates this formulation uses the non-drug affinity complex (DAC-free) version of CJC-1295, which lacks the Drug Affinity Complex (DAC) modification. This combination allows researchers to study the effects of two distinct peptide mechanisms on the GH/IGF-1 axis in controlled laboratory settings. CJC-1295 acts as a GHRH analog stimulating GH release, while Ipamorelin functions as a ghrelin receptor agonist with high selectivity for GH secretion.

Quality and Purity Standards

Both peptide components are independently manufactured and verified before combination. Each component is tested at ≥99% purity using HPLC analysis with mass spectrometry confirmation. The 5mg/5mg formulation undergoes additional quality testing to verify proper ratios. Every order includes Certificates of Analysis for both CJC-1295 and Ipamorelin, documenting purity levels, identity confirmation, and analytical data.

Research Applications and Mechanisms of Action

Research using CJC-1295+Ipamorelin focuses on the coordinated effects of GHRH analog and GHS receptor agonist stimulation. CJC-1295 (NO DAC) binds to the GHRH receptor on pituitary somatotroph cells, stimulating GH synthesis and release. Ipamorelin binds to the ghrelin receptor (GHS-R1a), potentiating GH secretion through a distinct mechanism. Research applications include:

Coordinate GH secretion dynamics in response to dual secretagogue stimulation
GHRH and GHS receptor signaling pathway interactions
Somatotroph cell function studies with combined secretagogue treatment
GH/IGF-1 axis modulation in controlled in vitro models
Comparative pharmacology of DAC-free versus DAC-modified GHRH analogs

Technical Specifications

Composition: CJC-1295 (NO DAC) 5mg + Ipamorelin 5mg
Purity: ≥99% per component (HPLC verified)
Physical Form: Lyophilized powder
Solubility: Soluble in sterile water, saline, or standard research buffers
Storage: -20°C in dry, light-protected conditions
Shelf Life: 24 months from manufacture date

Proper Storage and Handling Guidelines

Store the lyophilized powder at -20°C in a desiccated, light-protected environment. For reconstitution, use sterile water or 0.9% sodium chloride solution. Store reconstituted solutions at 2–8°C and use within two to four weeks.

Frequently Asked Questions

What is CJC-1295+Ipamorelin used for in research?
This combination is used to study the effects of GHRH analog and GHS receptor agonist stimulation on GH secretion dynamics and the GH/IGF-1 axis.

What does "NO DAC" mean in the formulation?
NO DAC indicates the CJC-1295 component lacks the Drug Affinity Complex modification, resulting in a shorter half-life profile compared to DAC-modified versions.

References and Further Reading

Researchers can consult literature on GHRH analogs (PMID: 16303850) and growth hormone secretagogues (PMID: 11502809) for background. All products are for research use only.