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TB-500

TB-500 at a glance

Peptide.Express TB-500 (CAS 77591-33-4) starts at $45, ≥99% pure by HPLC, with a molecular weight of 4963.4 Da and molecular formula C212H350N56O78S, third-party tested with a Certificate of Analysis you can verify before purchase. Ships same day on US orders placed before 2 PM EST, free over $150. For in-vitro laboratory research use only.

TB-500 — research-grade lyophilized peptide vial from Peptide.Express, ≥99% HPLC purity
≥99% PurityUS SynthesizedIn Stock

For laboratory research use only. Not for human or veterinary use.

Research-Grade Compound

TB-500 is the research-market name for synthetic Thymosin β-4 (Tβ4), an endogenous protein present in virtually all nucleated human cells at cytosolic concentrations of roughly 0.5 mM — one of the most abundant intracellular proteins there is. Molecular weight 4,963.4 Da, CAS 77591-33-4.

Purity standard: TB-500 is sourced to ≥99% by HPLC — sourcing spec. That is the specification every batch must meet, not a measurement of any one vial — the measured figure for a batch is on that batch's Certificate of Analysis.

1 · Select Size

10mg · $45.00/vial

$45.00$80.00ListUSD / Unit
1

Certificate of Analysis

No certificate on file yet for 10mg.

We do not show another size's Batch or accession here. Select a size with a published CoA, or check back once this presentation's lab report is posted.

HPLC VerifiedIdentity & purity
CoA Every OrderThird-party CoA
Ships Same DayBefore 2 PM EST
Free US ShipOrders over $150
BPC-157 + TB-500 Wolverine Stack research guide →

In-depth research overview, mechanism of action, and study applications.

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Safety Data Sheet (SDS)
≥99% by HPLCLC-MS/MS VerifiedCoA Every BatchIn-Vitro Research Use Only

TB-500 Specifications

Identity, purity and storage specifications for TB-500.
CompoundTB-500 (synthetic Thymosin β-4)
CAS77591-33-4
Molecular formulaC212H350N56O78S
Molecular weight4,963.4 Da
SequenceSynthetic Thymosin β-4 (43 aa, Ac-SDKPDMAEIEKFDKSKLKTETQEKNPLPSKETIEQEKQAGES) containing the LKKTET actin-binding motif
Purity≥99% by HPLC
FormLyophilized powder
Storage (lyophilized)-20°C, desiccated, protected from light
Storage (reconstituted)2–8°C, use within 14–28 days

Reconstituting TB-500: step-by-step peptide reconstitution guide. Concentration maths: peptide reconstitution calculator.

Buying TB-500 — Frequently Asked Questions

What purity standard does Peptide.Express use for TB-500?

≥99% by reverse-phase HPLC with LC-MS/MS confirming the 4,963.4 Da mass. Because TB-500 naming is inconsistent across the market, the mass confirmation on the CoA is the most useful field on the document — it tells you which molecule you actually have.

Where is the Certificate of Analysis for TB-500?

Available on this page and in the Peptide.Express lab results library. Each CoA is tied to a specific production batch and lists the HPLC chromatogram, mass spectrometry data, endotoxin result, testing laboratory and test date.

What testing does TB-500 undergo before shipping?

Reverse-phase HPLC for purity, LC-MS/MS for molecular weight identity, LAL endotoxin testing, and visual QC. All performed by an independent third-party laboratory, with a batch-specific Certificate of Analysis issued for each lot.

How should TB-500 be stored before and after reconstitution?

Lyophilized: -20°C, desiccated, light-protected, stable for 24 months. Reconstituted: 2–8°C, used within 14–28 days. Avoid repeated freeze-thaw cycles — larger peptides are more vulnerable to aggregation under thermal cycling than small ones.

Is TB-500 WADA prohibited?

Yes, at all times, both in and out of competition. TB-500 falls under WADA section S2 as a growth factor affecting tissue regeneration and angiogenesis.

TB-500 research reference

Research Compounds Related to TB-500

BPC-157The locally-acting VEGF counterpart studied alongside TB-500 in the Wolverine Stack.Wolverine BlendPre-blended BPC-157 + TB-500 in a single lyophilized vial.KLOW BlendFour-peptide formulation adding GHK-Cu and KPV to the BPC-157 + TB-500 base.BPC-157 + TB-500 KitSeparate vials for independent control of each compound.

All products are sold for in-vitro laboratory research use only. Not intended for human consumption, clinical use, or veterinary use. Peptide.Express makes no medical claims. Consult the published literature for research application guidance.

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