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Retatrutide

Retatrutide at a glance

Peptide.Express Retatrutide (CAS 2381089-83-2) starts at $65, ≥99% HPLC as the sourcing specification — not a measurement of any one vial — with a molecular weight of 4731 Da and molecular formula C221H342N46O68; measured purity and mass are only on that lot’s Certificate of Analysis you can verify before purchase. Ships same day on US orders placed before 2 PM EST, free over $150. For in-vitro laboratory research use only.

Retatrutide — research-grade lyophilized peptide vial from Peptide.Express, ≥99% HPLC purity
≥99% PurityUS SynthesizedIn Stock

For laboratory research use only. Not for human or veterinary use.

Retatrutide (INN; development code LY3437943; catalog name GLP3-RETA) is an investigational synthetic 39-amino-acid fatty-acylated peptide, CAS 2381089-83-2, average molecular weight 4,731 Da. One backbone agonizes GIPR, GLP-1R, and GCGR. It is not FDA-approved and is not a medicine. On this page, ≥99% HPLC is the sourcing specification every accepted lot must meet — not a measurement of any one vial. The measured purity and mass for a lot are only on that lot’s Certificate of Analysis. For in-vitro laboratory research use only. Not for human or veterinary use.

Purity standard: Retatrutide is sourced to ≥99% HPLC — sourcing spec. See how to read a peptide COA.

1 · Select Size

10mg · $65.00/vial

$65.00$85.00ListUSD / Unit
1

Certificate of Analysis

Showing CoA for 10mg.

Identity on CoA
GLP3-RT 10mg
HPLC (measured)
99.82%
Sourcing spec (separate line)
≥99% by HPLC
Lot
PX81126
Accession / CoA number
10954
Lab
Mistral Diagnostics
View CoAVerify with testing laboratory
HPLC VerifiedIdentity & purity
CoA Every OrderThird-party CoA
Ships Same DayBefore 2 PM EST
Free US ShipOrders over $150
Triple GIPR / GLP-1R / GCGR agonist research overview →

In-depth research overview, mechanism of action, and study applications.

Showing CoA for 10mg
Certificate Details
Accession / document id10954
Purity (measured)99.82%
Sourcing spec≥99% by HPLC
LotPX81126
Accession / CoA number10954
LabMistral Diagnostics
Methodology
HPLCLC-MS/MS
CAS Number2381089-83-2
Molecular Weight4731 g/mol
SequenceSynthetic 39-amino-acid GIP/GLP-1/glucagon triple agonist (fatty-acylated)
Verify Results with Testing Laboratory

Issued by an independent third-party laboratory; Peptide.Express does not test in-house. Results are reproduced as-is and confirm compound identity, purity, and the analytical methods used. For questions about specific results, contact support@peptide.express.

Safety Data Sheet (SDS)
≥99% by HPLCLC-MS/MS VerifiedCoA Every BatchIn-Vitro Research Use Only

Retatrutide Specifications

Identity, purity and storage specifications for Retatrutide.
CompoundRetatrutide
CAS2381089-83-2
Molecular formulaC221H342N46O68
Molecular weight4,731 Da
SequenceYAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS (39 residues; Aib 2 and 20, alpha-Me-Leu 13, C20 diacid on Lys17, C-terminal amide)
Purity≥99% by HPLC
FormLyophilized powder
Storage (lyophilized)-20°C, desiccated, protected from light
Storage (reconstituted)2–8°C, use within 14–28 days

Reconstituting Retatrutide: step-by-step peptide reconstitution guide. Concentration maths: peptide reconstitution calculator.

Buying Retatrutide — Frequently Asked Questions

What purity standard does Peptide.Express use for retatrutide?

≥99% by reverse-phase HPLC, measured as area-under-curve, with LC-MS/MS confirming mass against 4,731 Da. For a compound in this regulatory category the analytics carry more weight than usual: there is no pharmacopoeial monograph and no reference standard, so the chromatogram and the mass spectrum are the evidence.

Where is the Certificate of Analysis for retatrutide?

On this page, in the certificate panel above for the size this page opens on, and in the Peptide.Express lab results library. Read Lot, accession, measured HPLC, and the testing laboratory from that panel — they are printed on the certificate for the selected size. Match the lot on the vial to the lot on the CoA. If you select a size with no certificate on file, that size has no lot document yet — do not use another size's CoA. A Certificate of Analysis is a batch record, not a product-line brochure. For laboratory research use only. Not for human or veterinary use.

What testing does retatrutide undergo before shipping?

Reverse-phase HPLC for purity, LC-MS/MS for molecular weight identity confirmation, LAL endotoxin testing, and visual QC for appearance and particulate. Testing is performed by an independent third-party laboratory and reported on a batch-specific Certificate of Analysis.

How should retatrutide be stored before and after reconstitution?

Lyophilized: -20°C, desiccated and protected from light, stable for 24 months from manufacture. Reconstituted: 2–8°C, used within 14–28 days. Do not freeze the reconstituted solution. Acylated peptides aggregate under thermal cycling more readily than small unmodified ones, so repeated freeze-thaw is a real degradation route rather than a generic warning.

When do research-peptide orders ship?

US orders placed before 2 PM Eastern ship the same business day. Orders over $150 ship free inside the US. See the shipping page for the current policy. For laboratory research use only. Not for human or veterinary use.

Is retatrutide FDA approved?

No. Retatrutide is not approved by the FDA for any indication and is not approved by any other regulatory agency. This SKU is research-grade material. For in-vitro laboratory research use only. Not for human or veterinary use.

Retatrutide research reference

Research Compounds Related to Retatrutide

TirzepatideA dual GIPR / GLP-1R agonist. Two receptors on one backbone rather than three.TesamorelinGHRH analog studied on the visceral adipose and lipolysis side of metabolic research, through an entirely separate axis.MOTS-cMitochondrial-derived peptide studied for AMPK-mediated glucose uptake and fatty-acid oxidation.Bacteriostatic WaterBenzyl-alcohol-preserved sterile water, the standard diluent for reconstituting lyophilized acylated peptides.

All products are sold for in-vitro laboratory research use only. Not intended for human consumption, clinical use, or veterinary use. Peptide.Express makes no medical claims. Consult the published literature for research application guidance.

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