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Retatrutide (Reta / GLP-3 RT) — Research Peptide

Retatrutide at a glance

Retatrutide (LY3437943; CAS 2381089-83-2) is an investigational peptide. It is informally called "Reta" or "GLP-3 RT"; there is no hormone named GLP-3. Peptide.Express supplies it as lyophilized powder in 10, 20 and 30 mg vials with a ≥99% HPLC sourcing specification, and publishes each lot's third-party Certificate of Analysis. For laboratory research use only. Not for human or veterinary use.

Retatrutide — research-grade lyophilized peptide vial from Peptide.Express, ≥99% HPLC sourcing specification

10mg presentation shown.
Packaging reference.

$65.00$85.00ListUSD / vial
1. Select sizeAmount per vial
1
Lot PX-L916 · 99.94% HPLC (measured) · Freedom Diagnostics · 2026-09-24 · COAAll lots

For laboratory research use only. Not for human or veterinary use.

US fulfillmentSame-day dispatch before 2 PM Eastern.
Free US shipping over $150Shipping options and processing times

Purity standard: Retatrutide is sourced to ≥99% HPLC — sourcing spec. How to read a peptide COA.

Batch documentation

Certificate of Analysis

Your batch. Independently tested.

Measured results, batch identifiers, and the original laboratory report for your selected presentation.

10mg

The batch behind your vial.

Peptide.Express research material packaging illustration. Neutral unlabeled vial.Packaging illustration
Peptide.Express
Batch record summary
LOT / BATCH
PX-L916
COA ACCESSION
2609220039
Reported HPLC purity99.94%

Result for the selected batch.

Selected presentation
10mg
Laboratory
Freedom Diagnostics
View original CoA

Batch details

Sourcing specification
≥99% by HPLC
Accession / CoA
2609220039
Test Date
September 22, 2026
Laboratory
Freedom Diagnostics
Lot
PX-L916
Purity (measured)
99.94%
Net content
11.36 mg
Identity on CoA
Retatrutide 10mg
Reported
2026-09-24
HPLCLC-MS/MS

Issued by an independent third-party laboratory; Peptide.Express does not test in-house. Results are reproduced as-is and confirm compound identity, purity, and the analytical methods used.

How to match your vial to this report
  1. 1.Match the presentationRetatrutide · 10mg selected.
  2. 2.Match the batchMatch lot PX-L916 to your vial.
  3. 3.Open the original CoAAccession 2609220039. Review the original methods and results.
Explore the lab-results library

Certificates by vial size

SizeLotHPLC (measured)LaboratoryReport dateFile
5 mgR58182699.77%Mistral Diagnostics2026-08-29COA · Verify
10 mgPX-L91699.94%Freedom Diagnostics2026-09-24COA · Verify
15 mgPXC8162699.74%Mistral Diagnostics2026-08-14COA · Verify
20 mgPX-L91699.97%Freedom Diagnostics2026-09-24COA · Verify
30 mgPX-L91699.98%Freedom Diagnostics2026-09-24COA · Verify

Lot certificate of analysis · Safety data sheet

Names for this peptide

NameMeaningRefers to
LY3437943development code used in published literatureretatrutide
GLP-3informal nickname (no hormone named GLP-3 exists)retatrutide
GLP-3 RTshorthandretatrutide
RT3 / GLP3-R, GLP-R3shorthand variantsretatrutide
Retashorthandretatrutide

Continue exploring

Explore related compounds

Product information

Retatrutide Specifications

Visit the research library
Compound specifications
Compound
Retatrutide
CAS
2381089-83-2
Molecular formula
C221H342N46O68
Molecular weight
4,731 Da
Purity
≥99% HPLC specification
Form
Lyophilized powder
Storage (lyophilized)
-20°C, desiccated, protected from light
Storage (reconstituted)
2–8°C, use within 14–28 days
Sequence
View published sequence

YAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS (39 residues; Aib 2 and 20, alpha-Me-Leu 13, C20 diacid on Lys17, C-terminal amide)

Reconstituting Retatrutide: step-by-step peptide reconstitution guide. Concentration maths: peptide reconstitution calculator.

Research reference

Retatrutide research reference

One compound. Three research targets.

Research examines activity at GIP, GLP-1, and glucagon receptors. Explore the compound's mechanism and comparative research below.

Triple GIPR / GLP-1R / GCGR agonist research overview
Retatrutide receptor targetsA conceptual diagram connecting Retatrutide to GIPR, GLP-1R, GCGR. Not a molecular structure or potency comparison.GIPRGLP-1RGCGRRETATRUTIDELY3437943Triple-receptor agonist researchConceptual schematic · not to scale
Peptide.ExpressRESEARCH REFERENCE
Receptor pharmacology

Published research examines Retatrutide activity at GIP, GLP-1, and glucagon receptors.

Triple GIPR / GLP-1R / GCGR agonist research overviewWhat is retatrutide? Structure and research record
Comparative research

The research library

A closer look at the science.

Explore Retatrutide's identity, receptor activity, and published research.

Explore the research
Retatrutide research vial with research notes

Before you order

Buying Retatrutide — Frequently Asked Questions

What purity standard does Peptide.Express use for retatrutide?

Sourced to a ≥99% HPLC specification, measured as area-under-curve when a certificate reports it. Where a certificate reports a mass, compare it with 4,731 Da. For a compound in this regulatory category the analytics carry more weight than usual: there is no pharmacopoeial monograph and no reference standard, so the chromatogram and the mass spectrum are the evidence.

Where is the Certificate of Analysis for retatrutide?

On this page, in the certificate panel above for the size this page opens on, and in the Peptide.Express lab results library. Read Lot, accession, measured HPLC, and the testing laboratory from that panel — they are printed on the certificate for the selected size. Match the lot on the vial to the lot on the CoA. If you select a size with no certificate on file, that size has no lot document yet — do not use another size's CoA. A Certificate of Analysis is a batch record, not a product-line brochure. For laboratory research use only. Not for human or veterinary use.

What testing does retatrutide undergo before shipping?

Where a certificate is on file, it shows the assays that laboratory reported. Those can include reverse-phase HPLC, LC-MS/MS, an endotoxin result, and visual QC. A missing line is not a pass and is not proof the assay never ran.

How should retatrutide be stored before and after reconstitution?

Lyophilized: -20°C, desiccated and protected from light, stable for 24 months from manufacture. Reconstituted: 2–8°C, used within 14–28 days. Do not freeze the reconstituted solution. Acylated peptides aggregate under thermal cycling more readily than small unmodified ones, so repeated freeze-thaw is a real degradation route rather than a generic warning.

When do research-peptide orders ship?

US orders placed before 2 PM Eastern ship the same business day. Orders over $150 ship free inside the US. See the shipping page for the current policy. For laboratory research use only. Not for human or veterinary use.

Is retatrutide FDA approved?

No. Retatrutide is not approved by the FDA for any indication and is not approved by any other regulatory agency. This SKU is research-grade material. For in-vitro laboratory research use only. Not for human or veterinary use.

All products are sold for in vitro laboratory research use only. Not intended for human consumption, clinical use, or veterinary use. Peptide.Express makes no medical claims. Consult the published literature for research application guidance.

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Safety Data Sheet (SDS)

Catalog identity reference

Theoretical identity from the catalog or verified registry record — not a laboratory observation from the Certificate of Analysis above.

CAS Number
2381089-83-2
Molecular Formula
C221H342N46O68
Molecular Weight
4731 g/mol
Sequence
YAQGTFTSDYSILLDKKAQAAFIEYLLEGGPSSGAPPPS (39 residues; Aib at 2 and 20, alpha-Me-Leu at 13, C20 fatty diacid on Lys17 via gamma-Glu/AEEA linker, C-terminal amide)

What we can show you the numbers for

AOD 10MG and KPV 10MG vials