Tesamorelin vs CJC-1295 (No DAC)
Quick Answer
Tesamorelin and CJC-1295 (No DAC) are both GHRH (growth-hormone-releasing-hormone) analogs studied on the somatotropic axis. Tesamorelin is a stabilized 44-amino-acid GHRH analog with a longer research half-life; CJC-1295 (No DAC), or Modified GRF (1-29), is a short-acting 29-amino-acid analog often paired with Ipamorelin. Both are sold at Peptide.Express at ≥99% HPLC-verified purity for in-vitro research only.
Tesamorelin vs CJC-1295 (No DAC): At a Glance
| Attribute | Tesamorelin | CJC-1295 (No DAC) |
|---|---|---|
| Mechanism class | Long-acting GHRH analog | Short-acting GHRH analog (Mod GRF 1-29) |
| Peptide length | 44 amino acids (stabilized) | 29 amino acids |
| CAS number | 218949-48-5 | 863288-34-0 |
| Molecular weight | ~5135.9 Da | ~3367.9 Da |
| Research half-life | Extended | Short |
| Commonly studied with | Standalone GHRH research | Ipamorelin (ghrelin agonist) |
| Purity (Peptide.Express) | ≥99% HPLC verified | ≥99% HPLC verified |
How Tesamorelin and CJC-1295 (No DAC) Differ in Research
Tesamorelin and CJC-1295 (No DAC) are frequently compared in growth-hormone-secretagogue research because both are GHRH-receptor analogs, yet they differ in length, stability, and research half-life. Tesamorelin is a stabilized 44-amino-acid analog; CJC-1295 (No DAC) is the 29-amino-acid Modified GRF (1-29) fragment.
The practical research distinction is duration of action. The structural stabilization on Tesamorelin gives it a longer profile in study models, whereas CJC-1295 (No DAC) is short-acting, which is why it is so often investigated alongside the ghrelin-receptor agonist Ipamorelin to study two complementary GH-secretion pathways.
Both compounds are supplied by Peptide.Express at ≥99% HPLC-verified purity with a full Certificate of Analysis. All material is intended strictly for in-vitro laboratory research and educational use.
Frequently Asked Questions
What is the main difference between Tesamorelin and CJC-1295?
Both are GHRH analogs, but Tesamorelin is a longer, stabilized 44-amino-acid peptide with an extended research half-life, while CJC-1295 (No DAC) is the short-acting 29-amino-acid Modified GRF (1-29). For laboratory research use only.
Which is studied with Ipamorelin — Tesamorelin or CJC-1295?
CJC-1295 (No DAC) is the analog most commonly paired with Ipamorelin in research because its short action complements the ghrelin-receptor pathway Ipamorelin acts on.
Are Tesamorelin and CJC-1295 the same purity at Peptide.Express?
Yes — both are HPLC-verified at ≥99% purity by an independent third-party laboratory and ship with a Certificate of Analysis.