Buy MOTS-C + NAD KIT

MOTS-C + NAD Kit is a research-focused combination product that pairs the mitochondrial-derived peptide MOTS-C with the fundamental coenzyme NAD+ (nicotinamide adenine dinucleotide). This kit provides researchers with two complementary compounds for investigating mitochondrial biology, cellular energetics, and metabolic signaling pathways. MOTS-C is a 16-amino acid mitochondrial-derived peptide encoded by the mitochondrial 12S rRNA gene, while NAD+ is a ubiquitous coenzyme essential for cellular redox reactions, energy metabolism, and signaling processes including sirtuin activation and PARP function.

Quality and Purity Standards

Both MOTS-C and NAD+ components are independently manufactured and verified before kit assembly. MOTS-C is tested at ≥99% purity and NAD+ at ≥99% purity, both using HPLC analysis with mass spectrometry confirmation. Every order includes Certificates of Analysis for both components, documenting purity levels, identity confirmation, and batch-specific analytical data.

Research Applications and Mechanisms of Action

The MOTS-C + NAD Kit enables researchers to study two interconnected aspects of cellular metabolism. MOTS-C acts through AMPK activation, folate metabolism modulation, and nuclear gene regulation. NAD+ serves as a coenzyme for hundreds of enzymatic reactions, including sirtuins and PARPs. Combined research applications include:

Mitochondrial-nuclear communication studies using MOTS-C in conjunction with NAD+ modulation
Sirtuin activation assays examining NAD+ dependency and MOTS-C effects on cellular energetics
Cellular redox state analysis and NAD+/NADH ratio quantification
Mitochondrial function and bioenergetic profiling in cell-based models
Aging-related cellular metabolism studies

Technical Specifications

Composition: MOTS-C peptide + NAD+ coenzyme
Purity: ≥99% per component (HPLC verified)
Physical Form: Lyophilized powder
Storage: -20°C in dry, light-protected conditions
Shelf Life: 24 months from manufacture date

Proper Storage and Handling Guidelines

Store both components at -20°C in a desiccated, light-protected environment. Reconstitute each component separately using appropriate solvents. NAD+ is particularly sensitive to moisture and light; handle accordingly.

Frequently Asked Questions

What is the MOTS-C + NAD Kit used for in research?
This kit provides researchers with complementary tools for studying mitochondrial biology, cellular energetics, and the interconnected roles of mitochondrial-derived peptides and NAD+ metabolism.

What purity are the components?
Both MOTS-C and NAD+ are verified at ≥99% purity by HPLC analysis. Certificates of Analysis are included for each component.

References and Further Reading

Researchers can consult literature on MOTS-C biology (PMID: 26321659) and NAD+ metabolism (PMID: 33243848). Explore our MOTS-C research guide for additional context. All products are for research use only.