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Reference Entry

Verified chemical identity and bibliography.

PNC-27

For laboratory research use only. Not for human or veterinary use.

PNC-27 is registered as CAS 1159861-00-3, molecular formula C188H293N53O44S, average molecular weight 4,032 Da. Classified as: p53-derived membrane-active peptide studied in cancer cell models. Peptide.Express does not stock PNC-27.

PNC-27 Chemical Identity

PNC-27 chemical identity
PropertyValue
CAS number1159861-00-3
Molecular formulaC188H293N53O44S
Molecular weight4,032 Da
InChIKeyMZCACYLMMMXSKC-KOCFKOPYSA-N
PubChem CID16201774
CategoryMiscellaneous research peptides
AliasesPNC27

CANNOT_AUTO_VERIFY

Formula and mass for PNC-27 are registry values, not cross-checked against a sequence.

PNC-27 References

  1. PubChem CID 16201774chemical_identity
  2. CAS Common Chemistry 1159861-00-3chemical_identity
  3. HDM-2-Targeting Peptide PNC-27 Kills Cervical Cancer Cells but not Normal Cervical Cells.PMID 40750238 · literature
  4. Poptosis or Peptide-Induced Transmembrane Pore Formation: A Novel Way to Kill Cancer Cells without Affecting Normal Cells.PMID 38927351 · DOI 10.3390/biomedicines12061144 · literature
  5. Anti-Cancer Peptide PNC-27 Kills Cancer Cells by Unique Interactions with Plasma Membrane-Bound hdm-2 and with Mitochondrial Membranes Causing Mitochondrial Disruption.PMID 38802154 · literature
  6. Ketone Bodies Induce Unique Inhibition of Tumor Cell Proliferation and Enhance the Efficacy of Anti-Cancer Agents.PMID 37760956 · DOI 10.3390/biomedicines11092515 · literature

Provenance

Reviewed by Ben Laythee, Lead Chemist

PNC-27 Availability

Peptide.Express does not stock PNC-27.